Cerebral aspergilloma.

Introduction Over the last decade extra-pulmonary aspergillosis has been reported with increasing frequency from the Middle and Far East. In the late 60s, 17 cases of paranasal aspergilloma, some with orbital involvement, were reported from the Sudan; Aspergillus flavus was found to be the causative organism in all 17 (Miloshev et al., 1966, 1969). A further 60 cases have been described from North Sudan where A. flavus is a common organism in the soil (Mahgoub, 1977). Only 11 cases of solitary brain aspergilloma had been reported by 1977; 3 of these, including one due to A. flavus, occurred in Thailand (Visudhiphan, Bunyaratavej and Khantanaphar, 1973), 2 in India (Venugopal et al., 1977). Other aspergilli implicated in central nervous system infection have been A. fumigatus, A. oryzae, A. amstelodami, A. sydowi, A. glaucus, A. niger, A. candidus and A. versicolor. The present case describes an A. flavus infection of the brain in a young man from Saudi Arabia.